EIF3I

Eukaryotic translation initiation factor 3 subunit I (eIF3i) is a protein that in humans is encoded by the EIF3I gene.^[5][6][7]

EIF3I
Identifiers
Aliases	EIF3I, EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36, eukaryotic translation initiation factor 3 subunit I
External IDs	OMIM: 603911; MGI: 1860763; HomoloGene: 2786; GeneCards: EIF3I; OMA:EIF3I - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p35.2 Start 32,221,077 bp[1] End 32,245,397 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 D2.2|4 63.26 cM Start 129,485,753 bp[2] End 129,494,441 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans ganglionic eminence smooth muscle tissue gastrocnemius muscle rectum left adrenal gland right adrenal gland ventricular zone muscle of thigh left adrenal cortex Top expressed in endocardial cushion Paneth cell Rostral migratory stream internal carotid artery condyle atrioventricular valve external carotid artery vas deferens fossa human fetus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding translation initiation factor activity Cellular component extracellular exosome cytosol cytoplasm eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex, eIF3m eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex Biological process translational initiation protein biosynthesis formation of cytoplasmic translation initiation complex cytoplasmic translational initiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8668 54709 Ensembl ENSG00000084623 ENSMUSG00000028798 UniProt Q13347 Q9QZD9 RefSeq (mRNA) NM_003757 NM_001394168 NM_018799 RefSeq (protein) NP_003748 NP_061269 Location (UCSC) Chr 1: 32.22 – 32.25 Mb Chr 4: 129.49 – 129.49 Mb PubMed search [3] [4]
Wikidata
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Interactions

eIF3i has been shown to interact with TGF beta 1^[8] and eIF3a.^[6][9][10]

See also

• Eukaryotic initiation factor 3 (eIF3)