Envoplakin

Envoplakin is a protein that in humans is encoded by the EVPL gene.^[5][6][7]

EVPL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4QMD
Identifiers
Aliases	EVPL, EVPK, envoplakin
External IDs	OMIM: 601590; MGI: 107507; HomoloGene: 1506; GeneCards: EVPL; OMA:EVPL - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.1 Start 76,004,502 bp[1] End 76,027,306 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 E2 Start 116,111,385 bp[2] End 116,128,903 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen skin of leg mucosa of pharynx skin of arm gums oral cavity gingival epithelium skin of thigh epithelium of esophagus nipple Top expressed in esophagus lip epidermis hair follicle transitional epithelium of urinary bladder skin of external ear skin of abdomen skin of back conjunctival fornix cornea More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-macromolecule adaptor activity intermediate filament binding structural molecule activity cadherin binding Cellular component cell junction desmosome intermediate filament cytoskeleton extracellular exosome cytoskeleton cornified envelope cytoplasm cytosol intermediate filament membrane Biological process peptide cross-linking keratinization keratinocyte differentiation epidermis development cornification wound healing intermediate filament cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2125 14027 Ensembl ENSG00000167880 ENSMUSG00000034282 UniProt Q92817 Q9D952 RefSeq (mRNA) NM_001988 NM_001320747 NM_025276 RefSeq (protein) NP_001307676 NP_001979 NP_001307676.1 NP_079552 Location (UCSC) Chr 17: 76 – 76.03 Mb Chr 11: 116.11 – 116.13 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

Envoplakin has been shown to interact with PPL.^[8][9]

See also

• List of target antigens in pemphigus