GCC1

GRIP and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the GCC1 gene.^[5][6]

GCC1
Identifiers
Aliases	GCC1, GCC1P, GCC88, GRIP and coiled-coil domain containing 1
External IDs	OMIM: 607418; MGI: 1921625; HomoloGene: 11567; GeneCards: GCC1; OMA:GCC1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q32.1 Start 127,580,628 bp[1] End 127,593,611 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A3.3 Start 28,416,090 bp[2] End 28,428,389 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte islet of Langerhans granulocyte stromal cell of endometrium blood right testis left testis sperm nipple skin of thigh Top expressed in granulocyte supraoptic nucleus ascending aorta spermatocyte islet of Langerhans aortic valve stria vascularis spermatid jejunum transitional epithelium of urinary bladder More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 79571 74375 Ensembl ENSG00000179562 ENSMUSG00000029708 UniProt Q96CN9 Q9D4H2 RefSeq (mRNA) NM_024523 NM_028900 RefSeq (protein) NP_078799 NP_083176 Location (UCSC) Chr 7: 127.58 – 127.59 Mb Chr 6: 28.42 – 28.43 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport.^[6]

Interactions

GCC1 has been shown to interact with TRIM29.^[7]