GTF2E1

General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene.^[5]

GTF2E1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1VD4, 2JTX, 2RNQ, 2RNR, 5IY9, 5IYC, 5IYD, 5IY7, 5IYA, 5IY6, 5IYB, 5IY8
Identifiers
Aliases	GTF2E1, FE, TF2E1, TFIIE-A, general transcription factor IIE subunit 1
External IDs	OMIM: 189962; MGI: 1921447; HomoloGene: 38062; GeneCards: GTF2E1; OMA:GTF2E1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.33 Start 120,742,637 bp[1] End 120,783,069 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 B3 Start 37,330,152 bp[2] End 37,360,151 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte testicle gonad periodontal fiber sperm monocyte stromal cell of endometrium right adrenal cortex islet of Langerhans Top expressed in hand superior cervical ganglion otic vesicle endocardial cushion primitive streak medial ganglionic eminence abdominal wall atrioventricular valve iris trigeminal ganglion More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding sequence-specific DNA binding protein binding RNA polymerase II complex binding TFIIH-class transcription factor complex binding RNA polymerase II general transcription initiation factor activity Cellular component nucleus nucleoplasm transcription factor TFIID complex cytosol transcription preinitiation complex transcription factor TFIIE complex Biological process regulation of transcription, DNA-templated transcription by RNA polymerase II transcription, DNA-templated transcription initiation from RNA polymerase II promoter snRNA transcription by RNA polymerase II viral process transcription open complex formation at RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2960 74197 Ensembl ENSG00000153767 ENSMUSG00000022828 UniProt P29083 Q9D0D5 RefSeq (mRNA) NM_005513 NM_028812 NM_001355727 RefSeq (protein) NP_005504 NP_083088 NP_001342656 Location (UCSC) Chr 3: 120.74 – 120.78 Mb Chr 16: 37.33 – 37.36 Mb PubMed search [3] [4]
Wikidata
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See also

• Transcription factor II E