GTF2E2

General transcription factor IIE subunit 2 (GTF2E2), also known as transcription initiation factor IIE subunit beta (TFIIE-beta), is a protein that in humans is encoded by the GTF2E2 gene.^[5]

GTF2E2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1D8J, 1D8K, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Identifiers
Aliases	GTF2E2, FE, TF2E2, TFIIE-B, TTD6, general transcription factor IIE subunit 2
External IDs	OMIM: 189964; MGI: 1915403; HomoloGene: 37573; GeneCards: GTF2E2; OMA:GTF2E2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8p12 Start 30,578,318 bp[1] End 30,658,236 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 A4 Start 34,221,861 bp[2] End 34,267,201 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas right testis left testis Achilles tendon sperm gonad islet of Langerhans right adrenal gland right adrenal cortex stromal cell of endometrium Top expressed in otic placode saccule spermatid spermatocyte otic vesicle tail of embryo primitive streak somite genital tubercle abdominal wall More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding RNA binding TFIIH-class transcription factor complex binding RNA polymerase II general transcription initiation factor activity Cellular component nucleus transcription factor TFIIE complex nucleoplasm transcription factor TFIID complex cytosol nuclear speck Biological process transcription elongation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter regulation of transcription, DNA-templated transcription by RNA polymerase II transcription, DNA-templated snRNA transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2961 68153 Ensembl ENSG00000197265 ENSMUSG00000031585 UniProt P29084 Q9D902 RefSeq (mRNA) NM_002095 NM_001348353 NM_001167921 NM_001167922 NM_026584 RefSeq (protein) NP_002086 NP_001335282 NP_001161393 NP_001161394 NP_080860 Location (UCSC) Chr 8: 30.58 – 30.66 Mb Chr 8: 34.22 – 34.27 Mb PubMed search [3] [4]
Wikidata
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See also

• Transcription factor II E