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HIP2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

HIP2
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Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene.[5][6][7]

Quick Facts UBE2K, Available structures ...
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The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.[7]

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Interactions

HIP2 has been shown to interact with Huntingtin[5][8] and RNF2.[9]

References

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Further reading

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