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HOXB7

Protein-coding gene in humans From Wikipedia, the free encyclopedia

HOXB7
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Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.[5][6]

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Function

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.[7]

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Interactions

HOXB7 has been shown to interact with PBX1[8] and CREB-binding protein.[9]

See also

References

Further reading

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