ITIH1

Inter-alpha-trypsin inhibitor heavy chain H1 is a protein that in humans is encoded by the ITIH1 gene.^[5][6][7]

ITIH1
Identifiers
Aliases	ITIH1, H1P, IATIH, IGHEP1, ITI-HC1, ITIH, SHAP, inter-alpha-trypsin inhibitor heavy chain 1
External IDs	OMIM: 147270; MGI: 96618; HomoloGene: 1667; GeneCards: ITIH1; OMA:ITIH1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.1 Start 52,777,595 bp[1] End 52,792,068 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 B Start 30,651,137 bp[2] End 30,665,246 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver testicle gonad tibial arteries right coronary artery spleen monocyte left coronary artery granulocyte gallbladder Top expressed in left lobe of liver ankle joint proximal tubule sexually immature organism gallbladder right kidney yolk sac thoracic diaphragm right lobe of liver medial head of gastrocnemius muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptidase inhibitor activity calcium ion binding serine-type endopeptidase inhibitor activity protein binding Cellular component extracellular region blood microparticle extracellular exosome collagen-containing extracellular matrix Biological process negative regulation of peptidase activity negative regulation of endopeptidase activity hyaluronan metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3697 16424 Ensembl ENSG00000055957 ENSMUSG00000006529 UniProt P19827 Q61702 RefSeq (mRNA) NM_002215 NM_001166434 NM_001166435 NM_001166436 NM_008406 NM_001306078 RefSeq (protein) NP_001159906 NP_001159907 NP_001159908 NP_002206 NP_001293007 NP_032432 Location (UCSC) Chr 3: 52.78 – 52.79 Mb Chr 14: 30.65 – 30.67 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Inter-alpha-trypsin inhibitor
• ITIH2
• ITIH3
• ITIH4