ITIH3

Inter-alpha-trypsin inhibitor heavy chain H3 is a protein that in humans is encoded by the ITIH3 gene.^[5][6][7]

ITIH3
Identifiers
Aliases	ITIH3, H3P, ITI-HC3, SHAP, inter-alpha-trypsin inhibitor heavy chain 3
External IDs	OMIM: 146650; MGI: 96620; HomoloGene: 1669; GeneCards: ITIH3; OMA:ITIH3 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.1 Start 52,794,768 bp[1] End 52,809,009 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 B Start 30,630,529 bp[2] End 30,645,717 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver right coronary artery popliteal artery tibial arteries left coronary artery saphenous vein tibial nerve sural nerve spleen sperm Top expressed in ventromedial nucleus left lobe of liver dorsomedial hypothalamic nucleus paraventricular nucleus of hypothalamus lateral hypothalamus arcuate nucleus dorsal tegmental nucleus mammillary body ventral tegmental area medial vestibular nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptidase inhibitor activity endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding Cellular component extracellular exosome platelet dense granule lumen extracellular region Biological process negative regulation of peptidase activity hyaluronan metabolic process negative regulation of endopeptidase activity platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3699 16426 Ensembl ENSG00000162267 ENSMUSG00000006522 UniProt Q06033 Q61704 RefSeq (mRNA) NM_002217 NM_008407 RefSeq (protein) NP_002208 NP_032433 Location (UCSC) Chr 3: 52.79 – 52.81 Mb Chr 14: 30.63 – 30.65 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Inter-alpha-trypsin inhibitor
• ITIH1
• ITIH2
• ITIH4