KAT8 regulatory NSL complex subunit 1

KAT8 regulatory NSL complex subunit 1 is a protein that in humans is encoded by the KANSL1 gene.^[5][6]

KANSL1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4CY1, 4CY2
Identifiers
Aliases	KANSL1, KAT8 regulatory NSL complex subunit 1, NSL1, KIAA1267, MSL1v1, CENP-36, hMSL1v1, KDVS
External IDs	OMIM: 612452; MGI: 1923969; HomoloGene: 9140; GeneCards: KANSL1; OMA:KANSL1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.31 Start 46,029,916 bp[1] End 46,225,389 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 E1 Start 104,333,229 bp[2] End 104,468,861 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cell epithelium of colon thymus ganglionic eminence Achilles tendon sural nerve ventricular zone testicle cerebellar hemisphere pylorus Top expressed in tail of embryo genital tubercle zygote secondary oocyte visual cortex ventricular zone superior frontal gyrus primary visual cortex granulocyte neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K16 specific) protein binding histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase binding Cellular component histone acetyltransferase complex MLL1 complex chromosome, centromeric region nucleus kinetochore chromosome nucleoplasm NSL complex Biological process histone H4-K16 acetylation histone H4-K8 acetylation histone H4-K5 acetylation chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 284058 76719 Ensembl ENSG00000278458 ENSG00000275867 ENSG00000120071 ENSMUSG00000018412 UniProt Q7Z3B3 Q80TG1 RefSeq (mRNA) NM_001193465 NM_001193466 NM_015443 NM_001379198 NM_001081045 NM_001359634 NM_001372458 NM_001372459 NM_001372460 RefSeq (protein) NP_001180394 NP_001180395 NP_056258 NP_001366127 NP_001074514 NP_001346563 NP_001359387 NP_001359388 NP_001359389 Location (UCSC) Chr 17: 46.03 – 46.23 Mb Chr 11: 104.33 – 104.47 Mb PubMed search [3] [4]
Wikidata
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Interactions

KIAA1267 has been shown to interact with CCDC85B.^[7]

See also

• KAT8
• KAT8 regulatory NSL complex subunit 2
• KAT8 regulatory NSL complex subunit 3