KIF4B

KIF4B is a human protein encoded by the gene KIF4B. It is part of the kinesin family of motor proteins.

KIF4B
Identifiers
Aliases	KIF4B, kinesin family member 4B
External IDs	OMIM: 609184; HomoloGene: 129673; GeneCards: KIF4B; OMA:KIF4B - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q33.2 Start 155,013,755 bp[1] End 155,018,141 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle left testis ventricular zone right testis n/a More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule binding DNA binding nucleotide binding ATP binding plus-end-directed microtubule motor activity microtubule motor activity ATPase activity Cellular component nuclear matrix cytoplasm cytosol microtubule cytoskeleton kinesin complex nucleus nucleoplasm intercellular bridge Biological process mitotic cytokinesis microtubule-based movement antigen processing and presentation of exogenous peptide antigen via MHC class II mitotic spindle midzone assembly retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum mitotic spindle organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 285643 n/a Ensembl ENSG00000226650 n/a UniProt Q2VIQ3 n/a RefSeq (mRNA) NM_001099293 n/a RefSeq (protein) NP_001092763 n/a Location (UCSC) Chr 5: 155.01 – 155.02 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

KIF4B and the closely related protein KIF4A are essential for regulating anaphase spindle dynamics during mitosis.^[3]