MLLT10

Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.^[5][6]

MLLT10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5DAG, 5DAH
Identifiers
Aliases	MLLT10, AF10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, histone lysine methyltransferase DOT1L cofactor, MLLT10 histone lysine methyltransferase DOT1L cofactor
External IDs	OMIM: 602409; MGI: 1329038; HomoloGene: 20973; GeneCards: MLLT10; OMA:MLLT10 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p12.31 Start 21,524,646 bp[1] End 21,743,630 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 18,055,237 bp[2] End 18,212,388 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell epithelium of colon Achilles tendon right testis left testis secondary oocyte sperm tibia testicle skin of thigh Top expressed in spermatocyte genital tubercle tail of embryo secondary oocyte primary oocyte seminiferous tubule zygote neural layer of retina spermatid granulocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding chromatin binding nucleosome binding histone binding Cellular component nucleoplasm nucleus cytosol protein-containing complex Biological process regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8028 17354 Ensembl ENSG00000078403 ENSMUSG00000026743 UniProt P55197 O54826 RefSeq (mRNA) NM_001009569 NM_001195626 NM_001195627 NM_001195628 NM_001195630 NM_004641 NM_001324296 NM_001324297 NM_001252560 NM_001252561 NM_010804 RefSeq (protein) NP_001182555 NP_001182556 NP_001182557 NP_001182559 NP_001311225 NP_001311226 NP_004632 NP_001239489 NP_001239490 NP_034934 Location (UCSC) Chr 10: 21.52 – 21.74 Mb Chr 2: 18.06 – 18.21 Mb PubMed search [3] [4]
Wikidata
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Interactions

MLLT10 has been shown to interact with SS18.^[7]