MORF4L1

Mortality factor 4-like protein 1 is a protein that in humans is encoded by the MORF4L1 gene.^[5][6][7]

MORF4L1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2AQL, 2EFI, 2F5J, 2F5K, 2LKM, 2N1D
Identifiers
Aliases	MORF4L1, Eaf3, HsT17725, MEAF3, MORFRG15, MRG15, S863-6, FWP006, mortality factor 4 like 1
External IDs	OMIM: 607303; MGI: 1096551; HomoloGene: 86043; GeneCards: MORF4L1; OMA:MORF4L1 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q25.1 Start 78,810,487 bp[1] End 78,898,139 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 E3.1 Start 89,973,718 bp[2] End 89,996,827 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus Epithelium of choroid plexus pars compacta cerebellar vermis pars reticulata pons tibia germinal epithelium secondary oocyte caput epididymis Top expressed in tail of embryo olfactory bulb genital tubercle hypothalamus hippocampus proper testicle lung yolk sac neural tube ventricular zone More reference expression data BioGPS n/a
Gene ontology Molecular function protein N-terminus binding protein binding chromatin binding Cellular component nucleus nucleoplasm nuclear speck Sin3 complex NuA4 histone acetyltransferase complex histone acetyltransferase complex Biological process chromatin remodeling DNA recombination regulation of transcription, DNA-templated histone H2A acetylation transcription, DNA-templated cellular response to DNA damage stimulus double-strand break repair via homologous recombination histone H4 acetylation regulation of growth histone deacetylation DNA repair chromatin organization cell population proliferation histone acetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10933 21761 Ensembl ENSG00000185787 ENSMUSG00000062270 UniProt Q9UBU8 P60762 RefSeq (mRNA) NM_206839 NM_001265603 NM_001265604 NM_001265605 NM_006791 NM_001039147 NM_024431 NM_001357780 RefSeq (protein) NP_001252532 NP_001252533 NP_001252534 NP_006782 NP_996670 NP_001034236 NP_077751 NP_001344709 Location (UCSC) Chr 15: 78.81 – 78.9 Mb Chr 9: 89.97 – 90 Mb PubMed search [3] [4]
Wikidata
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Interactions

MORF4L1 has been shown to interact with MYST1,^[8] Retinoblastoma protein^[8][9] and MRFAP1.^[8][9]