MS4A7

Membrane-spanning 4-domains subfamily A member 7 is a protein that in humans is encoded by the MS4A7 gene.^[5][6][7]

MS4A7
Identifiers
Aliases	MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8, membrane spanning 4-domains A7
External IDs	OMIM: 606502; MGI: 1918846; HomoloGene: 10922; GeneCards: MS4A7; OMA:MS4A7 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.2 Start 60,378,485 bp[1] End 60,395,951 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 11,298,403 bp[2] End 11,313,510 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte spleen gallbladder appendix upper lobe of left lung granulocyte right lung rectum trabecular bone lower lobe of lung Top expressed in stroma of bone marrow interventricular septum calvaria internal carotid artery cervix external carotid artery mesenteric lymph nodes vestibular sensory epithelium thymus spleen More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 58475 109225 Ensembl ENSG00000166927 ENSMUSG00000024672 UniProt Q9GZW8 n/a RefSeq (mRNA) NM_206940 NM_021201 NM_206938 NM_206939 NM_001025610 NM_001276398 NM_027836 RefSeq (protein) NP_067024 NP_996821 NP_996822 NP_996823 n/a Location (UCSC) Chr 11: 60.38 – 60.4 Mb Chr 19: 11.3 – 11.31 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.^[7]