Membrane-spanning 4A

Membrane-spanning 4A genes are members of the CD20-like family. The MS4A genes are usually organized in a single genomic clusters in mammals, suggestive of gene duplication events.^[1] MS4A genes encode a class of four-transmembrane spanning proteins. MS4A genes have been described to act as a specific kind of olfactory receptor in the necklace olfactory sensory neurons in mice (Mus musculus).^[2]

In human (Homo sapiens) the members of this family include:

• MS4A1 (better known as "CD20")
• MS4A2
• MS4A3
• MS4A4A
• MS4A4E
• MS4A5
• MS4A6A
• MS4A6E
• MS4A7
• MS4A8
• MS4A9
• MS4A10
• MS4A12
• MS4A13
• MS4A14
• MS4A15
• MS4A18