MYCBP

C-Myc-binding protein is a protein that in humans is encoded by the MYCBP gene.^[5][6]

MYCBP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YY0
Identifiers
Aliases	MYCBP, AMY-1, MYC binding protein
External IDs	OMIM: 606535; MGI: 1891750; HomoloGene: 49312; GeneCards: MYCBP; OMA:MYCBP - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.3 Start 38,862,493 bp[1] End 38,873,368 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D2.2 Start 123,798,625 bp[2] End 123,806,062 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory zone of nasal mucosa gonad monocyte testicle mucosa of transverse colon right testis left testis rectum right uterine tube granulocyte Top expressed in genital tubercle zygote secondary oocyte tail of embryo olfactory epithelium Epithelium of choroid plexus primary oocyte seminiferous tubule yolk sac morula More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coactivator activity protein binding Cellular component cytoplasm nucleus mitochondrion Biological process regulation of transcription, DNA-templated transcription, DNA-templated spermatogenesis positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26292 56309 Ensembl ENSG00000214114 ENSMUSG00000028647 UniProt Q99417 Q9EQS3 RefSeq (mRNA) NM_012333 NM_019660 RefSeq (protein) NP_036465 NP_062634 Location (UCSC) Chr 1: 38.86 – 38.87 Mb Chr 4: 123.8 – 123.81 Mb PubMed search [3] [4]
Wikidata
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Function

The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.[supplied by OMIM]^[6]

Interactions

MYCBP has been shown to interact with AKAP1,^[7][8] C3orf15^[7] and Myc.^[5]