NE-CHMIMO

NE-CHMIMO (CHM-018) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB₁ receptor and has been sold online as a designer drug.^[1][2][3] NE-CHMIMO is the 1-cyclohexylmethyl (instead of 1-pentyl) analogue of the first-generation synthetic cannabinoid JWH-018. The corresponding cyclohexylmethyl derivative of JWH-081 had also been reported several months earlier.^[4]

NE-CHMIMO

Legal status
Legal status	CA: Schedule II DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B US: Schedule I Illegal in Japan
Identifiers
IUPAC name [1-(Cyclohexylmethyl)-1H-indol-3-yl](naphthalen-1-yl)methanone
CAS Number	1373876-11-9 Y
PubChem CID	139031057
ChemSpider	81407778
UNII	5FWB35TKQ2
CompTox Dashboard (EPA)	DTXSID401046437
Chemical and physical data
Formula	C26H25NO
Molar mass	367.492 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(c1cccc2ccccc12)c3cn(CC4CCCCC4)c5ccccc35
InChI InChI=1S/C26H25NO/c28-26(23-15-8-12-20-11-4-5-13-21(20)23)24-18-27(17-19-9-2-1-3-10-19)25-16-7-6-14-22(24)25/h4-8,11-16,18-19H,1-3,9-10,17H2 Key:HGJYPIZWMHHQKS-UHFFFAOYSA-N

Legal status

In the United States, all CB₁ receptor agonists of the 3-(1-naphthoyl)indole class such as NE-CHMIMO are Schedule I Controlled Substances.^[5]

NE-CHMIMO is a controlled substance in Japan as of November 2019.^[6]

See also

• AB-CHMINACA
• ADB-CHMINACA
• APP-CHMINACA
• CHM-081
• FUB-018
• MDMB-CHMICA
• MDMB-CHMINACA