PEX11B

Peroxisomal membrane protein 11B is a protein that in humans is encoded by the PEX11B gene.^[5][6] It is involved in the regulation of peroxisome abundance. ^[7]

PEX11B
Identifiers
Aliases	PEX11B, PEX11-BETA, PEX14B, peroxisomal biogenesis factor 11 beta, PEX11beta
External IDs	OMIM: 603867; MGI: 1338882; HomoloGene: 2852; GeneCards: PEX11B; OMA:PEX11B - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.1 Start 145,911,350 bp[1] End 145,918,717 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.1 Start 96,542,692 bp[2] End 96,552,682 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Brodmann area 9 internal globus pallidus palpebral conjunctiva cingulate gyrus right frontal lobe nucleus accumbens anterior cingulate cortex mucosa of transverse colon caudate nucleus Top expressed in spermatocyte spermatid right kidney dentate gyrus of hippocampal formation granule cell muscle of thigh lip entorhinal cortex primary visual cortex perirhinal cortex CA3 field More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein homodimerization activity Cellular component integral component of membrane peroxisomal membrane peroxisome extracellular exosome membrane integral component of peroxisomal membrane mitochondrion protein-containing complex Biological process regulation of peroxisome size peroxisome organization protein homooligomerization signal transduction peroxisome fission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8799 18632 Ensembl ENSG00000131779 ENSMUSG00000028102 UniProt O96011 Q9Z210 RefSeq (mRNA) NM_001184795 NM_003846 NM_001162387 NM_001162388 NM_011069 RefSeq (protein) NP_001171724 NP_003837 NP_001155859 NP_001155860 NP_035199 Location (UCSC) Chr 1: 145.91 – 145.92 Mb Chr 3: 96.54 – 96.55 Mb PubMed search [3] [4]
Wikidata
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Interactions

PEX11B has been shown to interact with PEX19.^[8][9]

Related gene problems

• 1q21.1 deletion syndrome
• 1q21.1 duplication syndrome