PEX19

Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene.^[5][6][7]

PEX19
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2W85, 2WL8, 3AJB, 3MK4
Identifiers
Aliases	PEX19, D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1, peroxisomal biogenesis factor 19
External IDs	OMIM: 600279; MGI: 1334458; HomoloGene: 134253; GeneCards: PEX19; OMA:PEX19 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.2 Start 160,276,807 bp[1] End 160,286,348 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 H3|1 79.54 cM Start 171,954,322 bp[2] End 171,964,060 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle Skeletal muscle tissue of biceps brachii ventricular zone epithelium of colon abdominal fat thoracic diaphragm subcutaneous adipose tissue islet of Langerhans right lobe of liver Top expressed in yolk sac tail of embryo lip muscle of thigh right kidney ventricular zone digastric muscle temporal muscle brown adipose tissue triceps brachii muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peroxisome membrane class-1 targeting sequence binding protein N-terminus binding ATPase binding protein binding Cellular component cytoplasm integral component of membrane cytosol membrane peroxisomal membrane peroxisome nucleoplasm brush border membrane nucleus protein-containing complex Biological process protein targeting to peroxisome peroxisome organization protein stabilization peroxisome membrane biogenesis peroxisome fission protein import into peroxisome membrane transmembrane transport establishment of protein localization to peroxisome negative regulation of lipid binding chaperone-mediated protein folding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5824 19298 Ensembl ENSG00000162735 ENSMUSG00000003464 UniProt P40855 Q8VCI5 RefSeq (mRNA) NM_001131039 NM_001193644 NM_002857 NM_001159525 NM_023041 NM_001356513 NM_001356514 RefSeq (protein) NP_001180573 NP_002848 NP_001152997 NP_075528 NP_001343442 NP_001343443 Location (UCSC) Chr 1: 160.28 – 160.29 Mb Chr 1: 171.95 – 171.96 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

PEX19 has been shown to interact with:

• ABCD1,^[8][9]
• ABCD2,^[8][9]
• ABCD3,^{[8][9][10][11]}
• PEX10,^[10][12]
• PEX11B,^[10][12]
• PEX12,^[10][12]
• PEX13,^[10][12]
• PEX16,^[12] and
• PEX3.^{[8][10][12][13]}