PFTK1

Serine/threonine-protein kinase PFTAIRE-1 is an enzyme that in humans is encoded by the CDK14 gene.^[5][6][7]

CDK14
Identifiers
Aliases	CDK14, PFTAIRE1, PFTK1, cyclin-dependent kinase 14, cyclin dependent kinase 14
External IDs	OMIM: 610679; MGI: 894318; HomoloGene: 7888; GeneCards: CDK14; OMA:CDK14 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.13 Start 90,466,424 bp[1] End 91,210,590 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 A1|5 2.61 cM Start 4,853,391 bp[2] End 5,470,312 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in postcentral gyrus Region I of hippocampus proper pars compacta pars reticulata lateral nuclear group of thalamus entorhinal cortex Brodmann area 10 superior frontal gyrus Brodmann area 46 tendon of biceps brachii Top expressed in cingulate gyrus habenula medial dorsal nucleus amygdala mammillary body dentate gyrus lateral geniculate nucleus anterior amygdaloid area pontine nuclei medial geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity cyclin-dependent protein serine/threonine kinase activity kinase activity protein serine/threonine kinase activity protein binding ATP binding cyclin binding Cellular component membrane plasma membrane cytoplasmic cyclin-dependent protein kinase holoenzyme complex nucleus cytoplasm cytosol Biological process phosphorylation regulation of canonical Wnt signaling pathway Wnt signaling pathway cell division protein phosphorylation G2/M transition of mitotic cell cycle cell cycle regulation of cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5218 18647 Ensembl ENSG00000058091 ENSMUSG00000028926 UniProt O94921 O35495 RefSeq (mRNA) NM_001287135 NM_001287136 NM_001287137 NM_012395 NM_011074 NM_001310448 RefSeq (protein) NP_001274064 NP_001274065 NP_001274066 NP_036527 NP_001297377 NP_035204 Location (UCSC) Chr 7: 90.47 – 91.21 Mb Chr 5: 4.85 – 5.47 Mb PubMed search [3] [4]
Wikidata
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Interactions

PFTK1 has been shown to interact with SEPT8.^[8]