POLR3E

DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene.^[5][6][7]

POLR3E
Identifiers
Aliases	POLR3E, RPC5, SIN, polymerase (RNA) III subunit E, RNA polymerase III subunit E, C37
External IDs	OMIM: 617815; MGI: 1349452; HomoloGene: 14052; GeneCards: POLR3E; OMA:POLR3E - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p12.2 Start 22,297,375 bp[1] End 22,335,101 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F2 Start 120,516,967 bp[2] End 120,546,655 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle muscle of thigh body of pancreas left lobe of thyroid gland anterior pituitary right lobe of thyroid gland skin of leg skin of abdomen right uterine tube left ovary Top expressed in right kidney proximal tubule human kidney epiblast hair follicle seminiferous tubule endothelial cell of lymphatic vessel condyle yolk sac Paneth cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-directed 5'-3' RNA polymerase activity RNA polymerase III activity Cellular component RNA polymerase III complex cytosol nucleus nucleoplasm Biological process immune system process defense response to virus transcription, DNA-templated transcription by RNA polymerase III innate immune response positive regulation of type I interferon production Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55718 26939 Ensembl ENSG00000284282 ENSG00000058600 ENSMUSG00000030880 UniProt Q9NVU0 Q9CZT4 RefSeq (mRNA) NM_001258033 NM_001258034 NM_001258035 NM_001258036 NM_018119 NM_001164096 NM_025298 NM_001379288 RefSeq (protein) NP_001244962 NP_001244963 NP_001244964 NP_001244965 NP_060589 NP_001157568 NP_079574 NP_001366217 Location (UCSC) Chr 16: 22.3 – 22.34 Mb Chr 7: 120.52 – 120.55 Mb PubMed search [3] [4]
Wikidata
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Interactions

POLR3E has been shown to interact with POLR3D.^[8]