PPP4R1

Serine/threonine-protein phosphatase 4 regulatory subunit 1 is an enzyme that in humans is encoded by the PPP4R1 gene.^[5][6]

PPP4R1
Identifiers
Aliases	PPP4R1, MEG1, PP4(Rmeg), PP4R1, protein phosphatase 4 regulatory subunit 1
External IDs	OMIM: 604908; MGI: 1917601; HomoloGene: 81737; GeneCards: PPP4R1; OMA:PPP4R1 - orthologs
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18p11.22 Start 9,546,791 bp[1] End 9,615,240 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 E1.1 Start 66,089,568 bp[2] End 66,148,921 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm gingival epithelium mucosa of pharynx visceral pleura Achilles tendon oral cavity amniotic fluid epithelium of colon ventricular zone nasal epithelium Top expressed in spermatid tail of embryo granulocyte intestinal villus primitive streak genital tubercle testicle Paneth cell vas deferens spermatocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding phosphoprotein phosphatase activity protein phosphatase regulator activity protein serine/threonine phosphatase activity Cellular component protein phosphatase 4 complex Biological process protein phosphorylation regulation of catalytic activity signal transduction protein dephosphorylation regulation of phosphoprotein phosphatase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9989 70351 Ensembl ENSG00000154845 ENSMUSG00000061950 UniProt Q8TF05 Q8K2V1 RefSeq (mRNA) NM_001042388 NM_005134 NM_001382562 NM_001114131 NM_146081 RefSeq (protein) NP_001035847 NP_005125 NP_001369491 NP_001107603 NP_666193 Location (UCSC) Chr 18: 9.55 – 9.62 Mb Chr 17: 66.09 – 66.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

PPP4R1 has been shown to interact with PPP4C.^[7][8][9]