RAB25

Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene.^[5][6] It is thought to act as a promoter of tumor development.^[7]

RAB25
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2OIL, 3TSO
Identifiers
Aliases	RAB25, CATX-8, RAB11C, member RAS oncogene family
External IDs	OMIM: 612942; MGI: 1858203; HomoloGene: 22995; GeneCards: RAB25; OMA:RAB25 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q22 Start 156,061,160 bp[1] End 156,070,504 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 88,449,336 bp[2] End 88,455,607 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon skin of abdomen skin of leg gums mucosa of pharynx gingival epithelium skin of thigh oral cavity rectum human penis Top expressed in transitional epithelium of urinary bladder lip esophagus epithelium of stomach left colon skin of external ear mucous cell of stomach cervix pyloric antrum duodenum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding myosin V binding protein binding GTPase activity Cellular component pseudopodium membrane plasma membrane cell projection pseudopodium extracellular exosome cytoplasmic vesicle membrane endosome recycling endosome Biological process protein transport regulation of vesicle-mediated transport positive regulation of epithelial cell migration epithelial cell morphogenesis positive regulation of cell population proliferation pseudopodium organization transport intracellular protein transport exocytosis Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57111 53868 Ensembl ENSG00000132698 ENSMUSG00000008601 UniProt P57735 Q9WTL2 RefSeq (mRNA) NM_020387 NM_016899 RefSeq (protein) NP_065120 NP_058595 Location (UCSC) Chr 1: 156.06 – 156.07 Mb Chr 3: 88.45 – 88.46 Mb PubMed search [3] [4]
Wikidata
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Interactions

RAB25 has been shown to interact with RAB11FIP2^[8][9] and RAB11FIP5.^[8][9]