RAB11FIP2

Rab11 family-interacting protein 2 is a protein that in humans is encoded by the RAB11FIP2 gene.^[5][6][7]

RAB11FIP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GZD, 2GZH, 2K6S, 3TSO, 4C4P
Identifiers
Aliases	RAB11FIP2, Rab11-FIP2, nRip11, RAB11 family interacting protein 2
External IDs	OMIM: 608599; MGI: 1922248; HomoloGene: 8937; GeneCards: RAB11FIP2; OMA:RAB11FIP2 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.11 Start 118,004,916 bp[1] End 118,046,941 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 D3 Start 59,891,316 bp[2] End 59,932,086 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in seminal vesicula tail of epididymis corpus epididymis caput epididymis postcentral gyrus entorhinal cortex skin of hip lateral nuclear group of thalamus superior frontal gyrus cardia Top expressed in nucleus accumbens piriform cortex temporal lobe olfactory tubercle Region I of hippocampus proper hand amygdala anterior amygdaloid area subiculum prefrontal cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein kinase binding protein homodimerization activity identical protein binding Cellular component membrane endosome recycling endosome membrane plasma membrane cytoplasmic vesicle membrane nucleoplasm intracellular membrane-bounded organelle phagocytic cup cell projection Biological process protein transport regulated exocytosis renal water homeostasis establishment of cell polarity insulin secretion involved in cellular response to glucose stimulus positive regulation of protein localization to plasma membrane phagocytosis TRAM-dependent toll-like receptor 4 signaling pathway positive regulation of GTPase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22841 74998 Ensembl ENSG00000107560 ENSMUSG00000040022 UniProt Q7L804 G3XA57 RefSeq (mRNA) NM_014904 NM_001330167 NM_001033172 NM_001164367 RefSeq (protein) NP_001317096 NP_055719 NP_001028344 NP_001157839 Location (UCSC) Chr 10: 118 – 118.05 Mb Chr 19: 59.89 – 59.93 Mb PubMed search [3] [4]
Wikidata
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Interactions

RAB11FIP2 has been shown to interact with MYO5B,^[8] RAB11A^[5][9][10] and RAB25.^[9][10]