RAB5C

Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene.^[5][6] RAB5C belongs to the Ras-related protein family.

RAB5C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4KYI
Identifiers
Aliases	RAB5C, L1880, RAB5CL, RAB5L, RABL, member RAS oncogene family
External IDs	OMIM: 604037; MGI: 105306; HomoloGene: 55533; GeneCards: RAB5C; OMA:RAB5C - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 42,124,978 bp[1] End 42,155,044 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 D|11 63.54 cM Start 100,605,835 bp[2] End 100,629,041 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte right lung upper lobe of left lung right adrenal cortex body of stomach left adrenal gland gallbladder right coronary artery right lobe of thyroid gland Top expressed in yolk sac granulocyte lip intestinal villus dentate gyrus of hippocampal formation granule cell Ileal epithelium superior frontal gyrus gastrula stroma of bone marrow primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GDP binding GTPase activity Cellular component melanosome lysosomal membrane endosome lipid droplet endocytic vesicle early endosome extracellular exosome membrane plasma membrane early endosome membrane azurophil granule membrane cytoplasmic vesicle anchored component of synaptic vesicle membrane intracellular anatomical structure Biological process protein transport regulation of endocytosis plasma membrane to endosome transport neutrophil degranulation transport intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5878 19345 Ensembl ENSG00000108774 ENSMUSG00000019173 UniProt P51148 P35278 RefSeq (mRNA) NM_001252039 NM_004583 NM_201434 NM_024456 NM_001305003 RefSeq (protein) NP_001238968 NP_004574 NP_958842 NP_001291932 NP_077776 Location (UCSC) Chr 17: 42.12 – 42.16 Mb Chr 11: 100.61 – 100.63 Mb PubMed search [3] [4]
Wikidata
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