SCAMP2

Secretory carrier-associated membrane protein 2 is a protein that in humans is encoded by the SCAMP2 gene.^[5][6]

SCAMP2
Identifiers
Aliases	SCAMP2, secretory carrier membrane protein 2
External IDs	OMIM: 606912; MGI: 1346518; HomoloGene: 4163; GeneCards: SCAMP2; OMA:SCAMP2 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q24.1 Start 74,843,730 bp[1] End 74,873,365 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 B Start 57,468,226 bp[2] End 57,496,078 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in rectum mucosa of transverse colon granulocyte islet of Langerhans minor salivary glands mucosa of ileum lymph node body of stomach right lung gallbladder Top expressed in spermatid granulocyte stroma of bone marrow corneal stroma epithelium of stomach tibiofemoral joint large intestine colon lip proximal tubule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integral component of membrane endosome recycling endosome membrane Golgi apparatus trans-Golgi network membrane extracellular exosome transport vesicle intracellular membrane-bounded organelle membrane Golgi membrane Biological process protein transport post-Golgi vesicle-mediated transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10066 24044 Ensembl ENSG00000140497 ENSMUSG00000040188 UniProt O15127 Q9ERN0 RefSeq (mRNA) NM_005697 NM_001320778 NM_022813 NM_001378928 RefSeq (protein) NP_001307707 NP_005688 NP_073724 NP_001365857 Location (UCSC) Chr 15: 74.84 – 74.87 Mb Chr 9: 57.47 – 57.5 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.^[6]