SH2D2A

SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.^[5][6]

SH2D2A
Identifiers
Aliases	SH2D2A, F2771, SCAP, TSAD, VRAP, SH2 domain containing 2A
External IDs	OMIM: 604514; MGI: 1351596; HomoloGene: 2958; GeneCards: SH2D2A; OMA:SH2D2A - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.1 Start 156,806,243 bp[1] End 156,816,848 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 F1|3 38.78 cM Start 87,754,062 bp[2] End 87,763,029 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte testicle blood gonad spleen appendix epithelium of colon lymph node apex of heart upper lobe of left lung Top expressed in thymus blood embryo mesenteric lymph nodes spleen subcutaneous adipose tissue hematopoietic cell granulocyte jejunum islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SH3 domain binding protein binding Cellular component cytoplasm cytosol Biological process multicellular organism development cell differentiation vascular endothelial growth factor receptor signaling pathway cell population proliferation angiogenesis signal transduction positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9047 27371 Ensembl ENSG00000027869 ENSMUSG00000028071 UniProt Q9NP31 Q9QXK9 RefSeq (mRNA) NM_001161441 NM_001161442 NM_001161443 NM_001161444 NM_003975 NM_001025571 NM_021309 RefSeq (protein) NP_001154913 NP_001154914 NP_001154915 NP_001154916 NP_003966 NP_001020742 NP_067284 Location (UCSC) Chr 1: 156.81 – 156.82 Mb Chr 3: 87.75 – 87.76 Mb PubMed search [3] [4]
Wikidata
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Interactions

SH2D2A has been shown to interact with MAP3K2.^[7]