SMEK2

Serine/threonine-protein phosphatase 4 regulatory subunit 3B is an enzyme that in humans is encoded by the SMEK2 gene.^[5][6][7]

PPP4R3B
Identifiers
Aliases	PPP4R3B, FLFL2, PP4R3B, PSY2, smk1, SMEK2, protein phosphatase 4 regulatory subunit 3B
External IDs	OMIM: 610352; MGI: 2144474; HomoloGene: 68886; GeneCards: PPP4R3B; OMA:PPP4R3B - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p16.1 Start 55,547,292 bp[1] End 55,618,880 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 A3.3 Start 29,172,890 bp[2] End 29,220,797 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell buccal mucosa cell jejunal mucosa ventricular zone Achilles tendon ganglionic eminence mucosa of paranasal sinus mucosa of sigmoid colon epithelium of colon tonsil Top expressed in saccule spermatocyte otic placode otic vesicle spermatid genital tubercle olfactory epithelium blood medullary collecting duct ventricular zone More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm centrosome protein phosphatase 4 complex cytoskeleton nucleus nucleoplasm microtubule organizing center nuclear speck Biological process regulation of lipid metabolic process protein dephosphorylation positive regulation of gluconeogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57223 104570 Ensembl ENSG00000275052 ENSMUSG00000020463 UniProt Q5MIZ7 Q922R5 RefSeq (mRNA) NM_001122964 NM_001282850 NM_020463 NM_134034 RefSeq (protein) NP_001116436 NP_001269779 NP_065196 NP_598795 NP_001350287 NP_001350288 NP_001350289 NP_001350290 NP_001350291 Location (UCSC) Chr 2: 55.55 – 55.62 Mb Chr 11: 29.17 – 29.22 Mb PubMed search [3] [4]
Wikidata
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Interactions

SMEK2 has been shown to interact with PPP4C.^[8][9][5]