STMN3

Stathmin-3 is a protein that in humans is encoded by the STMN3 gene.^[4][5][6]

STMN3
Identifiers
Aliases	STMN3, SCLIP, stathmin 3
External IDs	OMIM: 608362; MGI: 1277137; HomoloGene: 7528; GeneCards: STMN3; OMA:STMN3 - orthologs
Gene location (Mouse) Chr. Chromosome 2 (mouse)[1] Band 2|2 H4 Start 180,948,252 bp[1] End 180,956,293 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Pons middle temporal gyrus Brodmann area 23 endothelial cell superior vestibular nucleus nucleus accumbens entorhinal cortex Parietal Lobe cerebellar vermis postcentral gyrus Top expressed in facial motor nucleus motor neuron barrel cortex superior cervical ganglion pontine nuclei anterior horn of spinal cord medial vestibular nucleus dorsal tegmental nucleus prefrontal cortex subiculum More reference expression data BioGPS n/a
Gene ontology Molecular function protein domain specific binding tubulin binding Cellular component growth cone axon neuron projection Golgi apparatus cell projection cytoplasm cytosol Biological process microtubule depolymerization nervous system development regulation of microtubule polymerization or depolymerization regulation of GTPase activity cytoplasmic microtubule organization neuron projection development regulation of cytoskeleton organization negative regulation of Rac protein signal transduction blastocyst hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50861 20262 Ensembl n/a ENSMUSG00000027581 UniProt Q9NZ72 O70166 RefSeq (mRNA) NM_001276310 NM_015894 NM_009133 RefSeq (protein) NP_001263239 NP_056978 NP_033159 Location (UCSC) n/a Chr 2: 180.95 – 180.96 Mb PubMed search [2] [3]
Wikidata
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Function

The protein encoded by this gene belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.^[6]

Interactions

STMN3 has been shown to interact with TRPC5.^[7]