STRN3

Striatin-3 is a protein that in humans is encoded by the STRN3 gene.^[5][6][7]

STRN3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4N6J
Identifiers
Aliases	STRN3, SG2NA, PPP2R6B, striatin 3, S/G2NA
External IDs	OMIM: 614766; MGI: 2151064; HomoloGene: 82078; GeneCards: STRN3; OMA:STRN3 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 30,893,799 bp[1] End 31,026,401 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 B3 Start 51,656,415 bp[2] End 51,738,680 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon epithelium of colon biceps brachii sural nerve Skeletal muscle tissue of biceps brachii testicle tail of epididymis Skeletal muscle tissue of rectus abdominis gastrocnemius muscle muscle of thigh Top expressed in interventricular septum triceps brachii muscle temporal muscle ankle muscle of thigh medial head of gastrocnemius muscle intercostal muscle sternocleidomastoid muscle digastric muscle soleus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity protein phosphatase 2A binding protein binding calmodulin binding armadillo repeat domain binding protein-containing complex binding Cellular component cytoplasm soma plasma membrane Golgi apparatus dendrite protein phosphatase type 2A complex membrane nucleus nucleoplasm protein-containing complex FAR/SIN/STRIPAK complex Biological process response to estradiol negative regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29966 94186 Ensembl ENSG00000196792 ENSMUSG00000020954 UniProt Q13033 Q9ERG2 RefSeq (mRNA) NM_001083893 NM_014574 NM_001172098 NM_052973 NM_001364437 RefSeq (protein) NP_001077362 NP_055389 NP_001165569 NP_443205 NP_001351366 Location (UCSC) Chr 14: 30.89 – 31.03 Mb Chr 12: 51.66 – 51.74 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

STRN3 has been shown to interact with:

• CTTNBP2NL,^[8]
• CTTNBP2,^[8]
• FAM40A,^[8]
• MOBKL3,^[8]
• PDCD10,^[8]
• PPP2CA,^[8]
• PPP2R1A,^[8]
• RP6-213H19.1,^[8]
• STK24,^[8][9] and
• STRN.^[8]