STX7

Syntaxin-7 is a protein that in humans is encoded by the STX7 gene.^[5][6]

STX7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GL2
Identifiers
Aliases	STX7, syntaxin 7
External IDs	OMIM: 603217; MGI: 1858210; HomoloGene: 37823; GeneCards: STX7; OMA:STX7 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q23.2 Start 132,445,867 bp[1] End 132,513,198 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A4 Start 24,025,200 bp[2] End 24,066,120 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell monocyte tendon of biceps brachii Achilles tendon middle temporal gyrus ganglionic eminence amniotic fluid internal globus pallidus glomerulus secondary oocyte Top expressed in yolk sac dentate gyrus of hippocampal formation granule cell submandibular gland stroma of bone marrow right kidney trigeminal ganglion granulocyte conjunctival fornix barrel cortex substantia nigra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SNAP receptor activity protein binding chloride channel inhibitor activity syntaxin binding SNARE binding Cellular component integral component of membrane recycling endosome vesicle endosome late endosome early endosome membrane membrane tertiary granule plasma membrane endocytic vesicle lysosomal membrane SNARE complex azurophil granule early endosome immunological synapse perinuclear region of cytoplasm lysosome extracellular exosome synaptic vesicle endomembrane system Biological process positive regulation of receptor localization to synapse organelle localization positive regulation of T cell mediated cytotoxicity vesicle docking organelle assembly intracellular protein transport vesicle fusion vesicle-mediated transport regulation of protein localization to plasma membrane regulation of molecular function Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8417 53331 Ensembl ENSG00000079950 ENSMUSG00000019998 UniProt O15400 O70439 Q8BH40 RefSeq (mRNA) NM_003569 NM_001326578 NM_001326579 NM_001326580 NM_016797 NM_001358563 RefSeq (protein) NP_001313507 NP_001313508 NP_001313509 NP_003560 NP_058077 NP_001345492 Location (UCSC) Chr 6: 132.45 – 132.51 Mb Chr 10: 24.03 – 24.07 Mb PubMed search [3] [4]
Wikidata
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In melanocytic cells STX7 gene expression may be regulated by MITF.^[7]

Interactions

STX7 has been shown to interact with STX8,^[8] VPS18,^[9] Vesicle-associated membrane protein 8^[8][10] and VPS11.^[9]