SULT1A2

Sulfotransferase 1A2 is an enzyme that in humans is encoded by the SULT1A2 gene.^[5][6][7]

SULT1A2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1Z29
Identifiers
Aliases	SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2, sulfotransferase family 1A member 2, P-PST 2
External IDs	OMIM: 601292; MGI: 102896; HomoloGene: 128920; GeneCards: SULT1A2; OMA:SULT1A2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 28,591,943 bp[1] End 28,597,050 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 F3|7 69.25 cM Start 126,272,037 bp[2] End 126,275,604 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum mucosa of transverse colon right lobe of liver rectum testicle right lobe of thyroid gland left lobe of thyroid gland upper lobe of left lung right lung spleen Top expressed in left lobe of liver left colon tunica adventitia of aorta stroma of bone marrow white adipose tissue right lung lobe intercostal muscle subcutaneous adipose tissue muscle of thigh brown adipose tissue More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity sulfotransferase activity flavonol 3-sulfotransferase activity protein binding aryl sulfotransferase activity Cellular component cytoplasm cytosol Biological process steroid metabolic process phenol-containing compound metabolic process catecholamine metabolic process sulfation lipid metabolism amine biosynthetic process xenobiotic metabolic process ethanol catabolic process 3'-phosphoadenosine 5'-phosphosulfate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6799 20887 Ensembl ENSG00000197165 ENSMUSG00000030711 UniProt P50226 P52840 RefSeq (mRNA) NM_001054 NM_177528 NM_001363863 NM_133670 RefSeq (protein) NP_001045 NP_803564 NP_001350792 n/a Location (UCSC) Chr 16: 28.59 – 28.6 Mb Chr 7: 126.27 – 126.28 Mb PubMed search [3] [4]
Wikidata
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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities.

The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described.^[7]