SYT9

Synaptotagmin-9 is a protein that in humans is encoded by the SYT9 gene.^[5][6]

SYT9
Identifiers
Aliases	SYT9, synaptotagmin 9
External IDs	OMIM: 613528; MGI: 1926373; HomoloGene: 11062; GeneCards: SYT9; OMA:SYT9 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 7,238,778 bp[1] End 7,469,043 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E3 Start 106,969,935 bp[2] End 107,147,863 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus cerebellar vermis corpus callosum lateral nuclear group of thalamus subthalamic nucleus cerebellar hemisphere inferior ganglion of vagus nerve external globus pallidus ventral tegmental area pars reticulata Top expressed in habenula medial dorsal nucleus lumbar spinal ganglion medial geniculate nucleus molar Epithelium of choroid plexus lateral geniculate nucleus lobe of cerebellum cerebellar vermis superior cervical ganglion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium-dependent phospholipid binding metal ion binding clathrin binding calcium ion binding syntaxin binding identical protein binding phosphatidylserine binding phosphatidylinositol-4,5-bisphosphate binding SNARE binding Cellular component cytoplasmic vesicle integral component of membrane cell junction synapse dense core granule synaptic vesicle membrane secretory granule membrane membrane secretory granule plasma membrane clathrin-coated vesicle membrane integral component of synaptic vesicle membrane hippocampal mossy fiber to CA3 synapse exocytic vesicle Biological process regulation of insulin secretion positive regulation of calcium ion-dependent exocytosis regulation of calcium ion-dependent exocytosis vesicle fusion calcium ion-regulated exocytosis of neurotransmitter membrane organization calcium-dependent activation of synaptic vesicle fusion regulation of dopamine secretion synaptic vesicle exocytosis vesicle-mediated transport calcium-ion regulated exocytosis cellular response to calcium ion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 143425 60510 Ensembl ENSG00000170743 ENSMUSG00000062542 UniProt Q86SS6 Q9R0N9 RefSeq (mRNA) NM_175733 NM_021889 RefSeq (protein) NP_783860 NP_068689 Location (UCSC) Chr 11: 7.24 – 7.47 Mb Chr 7: 106.97 – 107.15 Mb PubMed search [3] [4]
Wikidata
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Interactions

SYT9 has been shown to interact with SYNCRIP,^[7] TUBB^[8] and TRPV1.^[9]