3-Phenylpiperidine

3-Phenylpiperidine is a chemical compound and cyclized phenethylamine.^[1] It can be thought of as β-phenethylamine with a propyl group connecting the amine and the β position.^[1]

3-Phenylpiperidine

Clinical data
ATC code	None
Identifiers
IUPAC name 3-phenylpiperidine
CAS Number	3973-62-4
PubChem CID	107207
ChemSpider	96476
ChEMBL	ChEMBL1196278
CompTox Dashboard (EPA)	DTXSID30871048
ECHA InfoCard	100.021.458
Chemical and physical data
Formula	C11H15N
Molar mass	161.248 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CC(CNC1)C2=CC=CC=C2
InChI InChI=1S/C11H15N/c1-2-5-10(6-3-1)11-7-4-8-12-9-11/h1-3,5-6,11-12H,4,7-9H2 Key:NZYBILDYPCVNMU-UHFFFAOYSA-N

According to Daniel Trachsel and colleagues in 2013, the pharmacology of 3-phenylpiperidine itself has not been reported, only its chemical synthesis has been described.^[1][2] 3-Phenylpiperidine was first described in the scientific literature by 1933.^[1][2]

Derivatives

3-Phenylpiperidine is a parent compound of several drugs such as the psychedelic and related drugs LPH-5 ((S)-2C-TFM-3PIP),^[3] 2C-B-3PIP, 2C-B-3PIP-NBOMe, 2C-B-3PIP-POMe, and Z3517967757 (Z7757),^[4] the antipsychotic OSU-6162,^[5] and the sigma receptor agonist 3-PPP.^[1]

See also

• Phenylpiperidines
• 4-Phenylpiperidine
• 2-Methyl-3-phenylpiperidine
• Phenmetrazine
• Substituted phenylmorpholine
• 1-Phenylpiperazine
• Partial ergoline