TMED2

Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene.^[4][5]

TMED2
Identifiers
Aliases	TMED2, P24A, RNP24, p24, p24b1, p24beta1, transmembrane p24 trafficking protein 2
External IDs	MGI: 3704329; HomoloGene: 55991; GeneCards: TMED2; OMA:TMED2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.31 Start 123,584,533 bp[1] End 123,598,582 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland corpus epididymis pylorus pericardium trachea caput epididymis cardia human penis superior surface of tongue Epithelium of choroid plexus n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component transport vesicle integral component of membrane ER to Golgi transport vesicle membrane Golgi apparatus Golgi membrane intracellular membrane-bounded organelle Golgi cisterna membrane zymogen granule membrane membrane endoplasmic reticulum endoplasmic reticulum membrane cytoplasmic vesicle membrane cytoplasmic vesicle COPI-coated vesicle endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum-Golgi intermediate compartment COPI-coated vesicle membrane COPII-coated ER to Golgi transport vesicle Biological process vesicle cargo loading neural tube closure maternal placenta development embryonic placenta development COPII vesicle coating endoplasmic reticulum to Golgi vesicle-mediated transport heart looping positive regulation of gene expression somitogenesis Golgi organization post-anal tail morphogenesis embryonic morphogenesis multicellular organism growth in utero embryonic development protein transport negative regulation of GTPase activity COPI coating of Golgi vesicle labyrinthine layer blood vessel development vesicle-mediated transport somite rostral/caudal axis specification intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10959 100862175 Ensembl ENSG00000086598 n/a UniProt Q15363 Q9R0Q3 RefSeq (mRNA) NM_006815 NM_001321445 XM_003945446 RefSeq (protein) NP_001308374 NP_006806 NP_062744 NP_001390182 NP_001390186 Location (UCSC) Chr 12: 123.58 – 123.6 Mb n/a PubMed search [2] [3]
Wikidata
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Interactions

TMED2 has been shown to interact with GORASP1^[6] and GORASP2.^[6]