TRIP10

Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene.^[5][6][7][8]

TRIP10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CT4, 2EFK, 2KE4
Identifiers
Aliases	TRIP10, CIP4, HSTP, STOT, STP, TRIP-10, thyroid hormone receptor interactor 10
External IDs	OMIM: 604504; MGI: 2146901; HomoloGene: 99728; GeneCards: TRIP10; OMA:TRIP10 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 6,737,925 bp[1] End 6,751,530 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 D Start 57,556,455 bp[2] End 57,570,665 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle gastric mucosa apex of heart ectocervix Descending thoracic aorta muscle layer of sigmoid colon right coronary artery ascending aorta right ovary Top expressed in interventricular septum muscle of thigh skeletal muscle tissue triceps brachii muscle lip temporal muscle ankle sternocleidomastoid muscle extraocular muscle digastric muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding lipid binding GTPase activator activity Cellular component cytoplasm cytosol Golgi apparatus cell projection intracellular membrane-bounded organelle membrane plasma membrane nucleoplasm cell cortex perinuclear region of cytoplasm lysosome phagocytic cup cytoskeleton extracellular exosome Biological process endocytosis cell communication regulation of small GTPase mediated signal transduction signal transduction positive regulation of GTPase activity actin cytoskeleton organization membrane organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9322 106628 Ensembl ENSG00000125733 ENSMUSG00000019487 UniProt Q15642 Q8CJ53 RefSeq (mRNA) NM_001288962 NM_001288963 NM_004240 NM_001242389 NM_001242390 NM_001242391 NM_134125 RefSeq (protein) NP_001275891 NP_001275892 NP_004231 NP_001229318 NP_001229319 NP_001229320 NP_598886 Location (UCSC) Chr 19: 6.74 – 6.75 Mb Chr 17: 57.56 – 57.57 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

TRIP10 has been shown to interact with STAT3,^[9] Wiskott-Aldrich syndrome protein,^[10] Huntingtin,^[11] CDC42,^[6][10] AKAP9^[12] and RHOQ.^[13]