TUBGCP3

Gamma-tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene.^[5][6][7] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

TUBGCP3
Identifiers
Aliases	TUBGCP3, 104p, GCP3, Grip104, SPBC98, Spc98, Spc98p, tubulin gamma complex associated protein 3, ALP6
External IDs	OMIM: 617818; MGI: 2183752; HomoloGene: 4609; GeneCards: TUBGCP3; OMA:TUBGCP3 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q34 Start 112,485,011 bp[1] End 112,588,205 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 A1.1 Start 12,664,277 bp[2] End 12,722,248 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte ventricular zone bone marrow cell ganglionic eminence right ovary left ovary gastric mucosa gonad testicle body of uterus Top expressed in Ileal epithelium tail of embryo ventricular zone genital tubercle thymus Gonadal ridge neural layer of retina cerebellar cortex granulocyte superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity structural constituent of cytoskeleton protein binding microtubule minus-end binding gamma-tubulin binding Cellular component cytoplasm cytosol centrosome spindle pole equatorial microtubule organizing center membrane spindle microtubule organizing center gamma-tubulin small complex polar microtubule spindle pole body centriole cytoskeleton microtubule gamma-tubulin complex Biological process centrosome duplication microtubule nucleation by interphase microtubule organizing center single fertilization mitotic spindle assembly cytoplasmic microtubule organization microtubule cytoskeleton organization microtubule nucleation meiosis mitotic cell cycle spindle assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10426 259279 Ensembl ENSG00000282003 ENSG00000126216 ENSMUSG00000000759 UniProt Q96CW5 P58854 RefSeq (mRNA) NM_001286277 NM_001286278 NM_001286279 NM_006322 NM_198031 RefSeq (protein) NP_001273206 NP_001273207 NP_001273208 NP_006313 NP_932148 Location (UCSC) Chr 13: 112.49 – 112.59 Mb Chr 8: 12.66 – 12.72 Mb PubMed search [3] [4]
Wikidata
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See also

• Tubulin
• TUBGCP2
• TUBGCP4
• TUBGCP5
• TUBGCP6