TUBGCP4

Tubulin, gamma complex associated protein 4 is a protein in humans that is encoded by the TUBGCP4 gene.^[5] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

TUBGCP4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3RIP
Identifiers
Aliases	TUBGCP4, 76P, GCP-4, GCP4, Grip76, MCCRP3, tubulin gamma complex associated protein 4
External IDs	OMIM: 609610; MGI: 1196293; HomoloGene: 8690; GeneCards: TUBGCP4; OMA:TUBGCP4 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q15.3 Start 43,369,221 bp[1] End 43,409,771 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 E5|2 60.37 cM Start 121,001,135 bp[2] End 121,029,251 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm secondary oocyte buccal mucosa cell ganglionic eminence ventricular zone gonad testicle tibialis anterior muscle epithelium of colon cerebellar hemisphere Top expressed in ascending aorta spermatocyte tail of embryo genital tubercle aortic valve supraoptic nucleus neural layer of retina internal carotid artery thymus spermatid More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of cytoskeleton microtubule minus-end binding protein binding gamma-tubulin binding Cellular component cytoplasm microtubule organizing center gamma-tubulin complex cytosol spindle pole body spindle pole recycling endosome equatorial microtubule organizing center membrane microtubule microtubule cytoskeleton cytoskeleton centrosome Biological process microtubule nucleation by interphase microtubule organizing center microtubule cytoskeleton organization mitotic spindle assembly centrosome duplication cytoplasmic microtubule organization microtubule nucleation meiosis mitotic cell cycle spindle assembly protein-containing complex assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27229 51885 Ensembl ENSG00000137822 ENSMUSG00000027263 UniProt Q9UGJ1 Q9D4F8 RefSeq (mRNA) NM_001286414 NM_014444 NM_001290824 NM_153387 RefSeq (protein) NP_001273343 NP_055259 NP_001277753 NP_700436 Location (UCSC) Chr 15: 43.37 – 43.41 Mb Chr 2: 121 – 121.03 Mb PubMed search [3] [4]
Wikidata
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See also

• Tubulin
• TUBGCP2
• TUBGCP3
• TUBGCP5
• TUBGCP6