Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution holds that all species are related and gradually change over generations. In a population, the genetic variations affect the phenotypes (physical characteristics) of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed on to their offspring. Some examples of evolution in species over many generations are the peppered moth and flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology.
Venom in snakes and some lizards is a form of saliva that has been modified into venom over its evolutionary history. In snakes, venom has evolved to kill or subdue prey, as well as to perform other diet-related functions. While snakes occasionally use their venom in self defense, this is not believed to have had a strong effect on venom evolution. The evolution of venom is thought to be responsible for the enormous expansion of snakes across the globe.
The evolutionary history of snake venom is a matter of debate. Historically, snake venom was believed to have evolved once, at the base of the Caenophidia, or derived snakes. Molecular studies published beginning in 2006 suggested that venom originated just once among a putative clade of reptiles, called Toxicofera, approximately 170 million years ago. Under this hypothesis, the original toxicoferan venom was a very simple set of proteins that were assembled in a pair of glands. Subsequently, this set of proteins diversified in the various lineages of toxicoferans, including Serpentes, Anguimorpha, and Iguania: several snake lineages also lost the ability to produce venom. The Toxicoferan hypothesis was challenged by studies in the mid-2010s, including a 2015 study which found that venom proteins had homologs in many other tissues in the Burmese python. The study therefore suggested that venom had evolved independently in different reptile lineages, including once in the Caenophid snakes. Venom containing most extant toxin families is believed to have been present in the last common ancestor of the Caenophidia: these toxins subsequently underwent tremendous diversification, accompanied by changes in the morphology of venom glands and delivery systems. (Full article...)
Image 7Turing's 1952 paper explained mathematically how patterns such as stripes and spots, as in the giant pufferfish, may arise, without molecular evidence. (from Evolutionary developmental biology)
Image 9Gap genes in the fruit fly are switched on by genes such as bicoid, setting up stripes across the embryo which start to pattern the body's segments. (from Evolutionary developmental biology)
Image 15Five types of chromosomal mutations (from Mutation)
Image 16Speciation via polyploidy: A diploid cell undergoes failed meiosis, producing diploid gametes, which self-fertilize to produce a tetraploid zygote. In plants, this can effectively be a new species, reproductively isolated from its parents, and able to reproduce. (from Speciation)
Image 19A mutation has caused this moss rose plant to produce flowers of different colors. This is a somatic mutation that may also be passed on in the germline. (from Mutation)
Image 20This figure shows a simplified version of loss-of-function, switch-of-function, gain-of-function, and conservation-of-function mutations. (from Mutation)
Image 28The distribution of fitness effects (DFE) of mutations in vesicular stomatitis virus. In this experiment, random mutations were introduced into the virus by site-directed mutagenesis, and the fitness of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous. (from Mutation)
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