1D-LSD

1D-LSD, also known as 1-(1,2-dimethylcyclobutane-1-carbonyl)-LSD or as SYN-L-229, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is believed to be a prodrug of LSD and has replaced 1V-LSD in Germany after 1V-LSD became covered by the German NpSG law in 2022.^[1]

1D-LSD

Clinical data
Other names	1-(1,2-Dimethylcyclobutane-1-carbonyl)-LSD; 1-(1,2-Dimethylcyclobutane-1-carbonyl)-N,N-diethyllysergamide; SYN-L-229
Routes of administration	Oral
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Identifiers
IUPAC name (8β)-1-(1,2-Dimethylcyclobutane-1-carbonyl)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide
PubChem CID	170703347
Chemical and physical data
Formula	C27H35N3O2
Molar mass	433.596 g·mol−1
3D model (JSmol)	Interactive image
SMILES [H][C@@]12CC3=CN(C(=O)C4(C)CCC4C)C4=C3C(=CC=C4)C1=C[C@H](CN2C)C(=O)N(CC)CC
InChI InChI=1S/C27H35N3O2/c1-6-29(7-2)25(31)19-13-21-20-9-8-10-22-24(20)18(14-23(21)28(5)15-19)16-30(22)26(32)27(4)12-11-17(27)3/h8-10,13,16-17,19,23H,6-7,11-12,14-15H2,1-5H3/t17?,19-,23-,27?/m1/s1 Key:RNVFVHAKGPSAIU-ZRCBXKLVSA-N

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Society and culture

Legal status

Austria

According to the current legal situation, 1D-LSD is neither explicitly mentioned in the Narcotic Drugs Ordinance nor in the Psychotropic Substances Ordinance (SV/PV), thus it is neither to be classified as a narcotic drug in the sense of the SV nor as a psychotropic substance in the sense of the PV.

Germany

Since the 14 June 2024 1D-LSD (and 1T-LSD) are covered by the German NpSG law.

See also

• Substituted lysergamide
• 1S-LSD
• 1DD-LSD
• 1V-LSD
• 1cP-LSD
• 1T-LSD
• Lizard Labs