2C-TFE

2C-TFE, also known as 4-(2,2,2-trifluoroethyl)-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug of the phenethylamine and 2C families related to 2C-E and 2C-TFM.^[2][1] It was first synthesised by Daniel Trachsel, and is reportedly a potent psychedelic with an active dose in the 5 to 15 mg range orally, and a long duration of 12 to 24 hours.^{[2][1]: 769–771}

2C-TFE

Clinical data
Other names	4-(2,2,2-Trifluoroethyl)-2,5-dimethoxyphenethylamine
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Pharmacokinetic data
Duration of action	12–24 hours[1]
Identifiers
IUPAC name 2-[2,5-dimethoxy-4-(2,2,2-trifluoroethyl)phenyl]ethan-1-amine
PubChem CID	57498513
CompTox Dashboard (EPA)	DTXSID301336578
Chemical and physical data
Formula	C12H16F3NO2
Molar mass	263.260 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1CCN)OC)CC(F)(F)F
InChI InChI=1S/C12H16F3NO2/c1-17-10-6-9(7-12(13,14)15)11(18-2)5-8(10)3-4-16/h5-6H,3-4,7,16H2,1-2H3 Key:DVENUPQPPXYSLN-UHFFFAOYSA-N

See also

• 2C (psychedelics)
• 2C-EF
• 2C-TFM
• 2C-T-TFM
• 3C-DFE
• DOTFE
• DOTFM
• Trifluoromescaline