5F-AB-PINACA

Not to be confused with 5F-APINACA.

5F-AB-PINACA is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication, and has been sold online as a designer drug.^[1][2]

5F-AB-PINACA

Legal status
Legal status	CA: Schedule II DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B US: Schedule I Illegal in China and Singapore
Identifiers
IUPAC name N-[(2S)-1-Amino-3-methyl-1-oxobutan-2-yl]-1-(5-fluoropentyl)indazole-3-carboxamide
CAS Number	1800101-60-3
PubChem CID	91936927
ChemSpider	29763723
UNII	3L83B2298V
CompTox Dashboard (EPA)	DTXSID401009970
Chemical and physical data
Formula	C18H25FN4O2
Molar mass	348.422 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)[C@H](NC(=O)c1nn(CCCCCF)c2ccccc12)C(N)=O
InChI InChI=1S/C18H25FN4O2/c1-12(2)15(17(20)24)21-18(25)16-13-8-4-5-9-14(13)23(22-16)11-7-3-6-10-19/h4-5,8-9,12,15H,3,6-7,10-11H2,1-2H3,(H2,20,24)(H,21,25)/t15-/m0/s1 Key:WCBYXIBEPFZUBG-HNNXBMFYSA-N

5F-AB-PINACA has been reported to be a potent agonist of the CB₁ receptor and CB₂ receptor with EC₅₀ values of 0.48 nM and 2.6 nM respectively.^[3] Its metabolism has been described in literature.^[4][5]

Legality

China

As of October 2015 5F-AB-PINACA is a controlled substance in China.^[6]

Germany

5F-AB-PINACA is an Anlage II controlled substance in Germany as of May 2015.^[7]

Singapore

It is also controlled under the Fifth Schedule of the Misuse of Drugs Act (MDA) in Singapore as of May 2015.^[8]

See also

• 5F-ADB
• 5F-AMB
• 5F-CUMYL-PINACA
• AB-FUBINACA
• AB-CHFUPYCA
• AB-PINACA
• ADB-CHMINACA
• ADB-FUBINACA
• ADB-PINACA
• ADBICA
• APICA
• APINACA
• MDMB-CHMICA
• PX-3