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ADB-PINACA
Chemical compound From Wikipedia, the free encyclopedia
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ADB-PINACA is a cannabinoid designer drug that is an ingredient in some synthetic cannabis products. It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.52 nM and 0.88 nM respectively.[1][2] Like MDMB-FUBINACA, this compound incorporates the unnatural amino acid tert-leucine.
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Side effects
ADB-PINACA has been linked to multiple hospitalizations and deaths due to its use.[3][4][5]
Metabolism
Nineteen ADB-PINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic reactions included pentyl hydroxylation, hydroxylation followed by oxidation (ketone formation), and glucuronidation.[6]
Legality
ADB-PINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[7]
In the United States, it is a Schedule I controlled substance.[8] but its 5'-bromo analog ADB-5'Br-PINACA is not as of October 20th, 2023.
As of October 2015 ADB-PINACA is a controlled substance in China.[9]
See also
References
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