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5F-APINACA
Chemical compound From Wikipedia, the free encyclopedia
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5F-APINACA (also known as A-5F-PINACA,[3] 5F-AKB-48 or 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.[4][5] Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the corresponding pentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4.[6]
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5F-APINACA was first identified in South Korea.[7] It is expected to be a potent agonist of the CB1 receptor and CB2 receptor.[8] Its metabolism has been described in literature.[9][10][11][12]
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Pharmacology
5F-APINACA acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.[13]
Legality
In the United States, 5F-APINACA is a Schedule I controlled substance.[14]
5F-APINACA is an Anlage II controlled drug in Germany since July 2013.
As of October 2015, 5F-APINACA is a controlled substance in China.[15]
5F-APINACA is banned in the Czech Republic.[16]
See also
References
External links
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