CD3EAP

DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.^[5][6][7][8]

POLR1G
Identifiers
Aliases	POLR1G, ASE-1, ASE1, CAST, PAF49, CD3e molecule associated protein, RPA34, RNA polymerase I subunit G, CD3EAP
External IDs	OMIM: 107325; MGI: 1917583; HomoloGene: 17107; GeneCards: POLR1G; OMA:POLR1G - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.32 Start 45,406,644 bp[1] End 45,410,737 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 A3 Start 19,089,939 bp[2] End 19,093,408 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad oocyte secondary oocyte testicle mucosa of urinary bladder tibialis anterior muscle buccal mucosa cell gingival epithelium gastrocnemius muscle endothelial cell Top expressed in otic vesicle hand internal carotid artery fossa external carotid artery epiblast Paneth cell condyle muscle of thigh embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-directed 5'-3' RNA polymerase activity RNA binding Cellular component RNA polymerase I complex RNA polymerase I transcription regulator complex mitochondrion nucleus nucleoplasm chromosome fibrillar center nucleolus cytosol Biological process transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription epigenetic maintenance of chromatin in transcription-competent conformation rRNA transcription transcription elongation from RNA polymerase I promoter transmembrane receptor protein tyrosine kinase signaling pathway transcription by RNA polymerase I Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10849 70333 Ensembl ENSG00000117877 ENSMUSG00000047649 UniProt O15446 Q76KJ5 RefSeq (mRNA) NM_012099 NM_001297590 NM_145822 RefSeq (protein) NP_001284519 NP_036231 NP_665821 Location (UCSC) Chr 19: 45.41 – 45.41 Mb Chr 7: 19.09 – 19.09 Mb PubMed search [3] [4]
Wikidata
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Interactions

CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain,^[5] POLR1E^[7] and POLR1C.^[7]