Daf-3

The DAF-3 or Dwarfin sma is a nematode Caenorhabditis elegans gene encoding a Co-SMAD protein of TGF-beta signaling pathway. Without daf-7 signal, DAF-3 combined with transcription factor daf-5 to form a heterodimer and started dauer development. When daf-7 binds to the receptors daf-1/daf-4, the phosphorylated daf-8/daf-14 heterodimer enter to the nucleus to inhibit this transcription.^[1]

Dwarfin sma
Identifiers
Organism	Caenorhabditis elegans
Symbol	daf-3
Entrez	180431
RefSeq (mRNA)	NM_075760.6
RefSeq (Prot)	NP_508161.3
UniProt	Q95QI7
Other data
Chromosome	X: 0.82 - 0.83 Mb
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