EIF3G

Eukaryotic translation initiation factor 3 subunit G (eIF3g) is a protein that in humans is encoded by the EIF3G gene.^[5][6]

EIF3G
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CQ0, 2MJC, 5K0Y
Identifiers
Aliases	EIF3G, EIF3-P42, EIF3S4, eIF3-delta, eIF3-p44, eukaryotic translation initiation factor 3 subunit G
External IDs	OMIM: 603913; MGI: 1858258; HomoloGene: 2784; GeneCards: EIF3G; OMA:EIF3G - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 10,115,014 bp[1] End 10,119,918 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A3 Start 20,805,645 bp[2] End 20,809,919 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte body of pancreas left ovary left testis right testis gastrocnemius muscle right ovary canal of the cervix body of stomach Achilles tendon Top expressed in primitive streak mandibular prominence Gonadal ridge maxillary prominence vas deferens condyle hair follicle abdominal wall epiblast medullary collecting duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding translation initiation factor activity nucleic acid binding RNA binding Cellular component cytoplasm perinuclear region of cytoplasm eukaryotic translation initiation factor 3 complex nucleus cytosol eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex Biological process translational initiation viral translational termination-reinitiation protein biosynthesis formation of cytoplasmic translation initiation complex cytoplasmic translational initiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8666 53356 Ensembl ENSG00000130811 ENSMUSG00000070319 UniProt O75821 Q9Z1D1 RefSeq (mRNA) NM_003755 NM_016876 RefSeq (protein) NP_003746 NP_058572 Location (UCSC) Chr 19: 10.12 – 10.12 Mb Chr 9: 20.81 – 20.81 Mb PubMed search [3] [4]
Wikidata
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Interactions

EIF3G has been shown to interact with Band 4.1,^[7] EIF3C^[5][8] and EIF3A.^[5][9]

See also

• Eukaryotic initiation factor 3 (eIF3)