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Insecticide Resistance Action Committee

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The Insecticide Resistance Action Committee (IRAC) was formed in 1984 and works as a specialist technical group of the industry association CropLife to be able to provide a coordinated industry response to prevent or delay the development of insecticide resistance in insect, mite and nematode pests. IRAC strives to facilitate communication and education on insecticide and traits resistance as well as to promote the development and facilitate the implementation of insecticide resistance management strategies.[1]

IRAC is recognised by the Food and Agriculture Organization (FAO) and the World Health Organization (WHO) of the United Nations as an advisory body on matters pertaining to insecticide resistance.[2]

Pesticideresistance.org is a database financed by IRAC, US Department of Agriculture, and others.[3]

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Sponsors

IRAC's sponsors are: ADAMA, BASF, Bayer CropScience, Corteva, FMC, Mitsui Chemicals, Nihon Nohyaku, Sumitomo Chemical, Syngenta and UPL.[4]

Mode of action classification

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IRAC publishes an insecticide mode of action (MoA) classification that lists most common insecticides and acaricides and recommends that "successive generations of a pest should not be treated with compounds from the same MoA Group".[5][6] IRAC assigns a mode of action (MoA) to an insecticide, based on sufficient scientific data.[7] They then update the mode of action (MoA) classification.[5] Several insecticides and classes of insecticide may act through the same mode of action.[8]

Classes of Insecticide

If an insecticide is successful, follow-on insecticides, based on the chemical structure of the first in class (prototype) insecticide, may be developed either by the original company or by competitors. Sought after are insecticides which have improved properties or which kill different orders or species of insect. The resulting classes of insecticides are named by IRAC after common usage has been established, although alternative names may be found in the scientific literature.

Table of modes of action and classes of insecticide

In the table the number of insecticides listed in each class is given, and an example of each class. The number of insecticides in the IRAC class listing as of 2024 is given in column Nr (A). The number in the Compendium of Pesticide Common Names[9] (insecticide + acaricide) is given in column Nr (B), although the name given there to the class historically is often different to the IRAC class name.

More information IRAC code, Mode of action ...
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See also

Further reading

  • Casida, John E. (2012). "The Greening of Pesticide–Environment Interactions: Some Personal Observations". Environmental Health Perspectives. 120 (4): 487–493. doi:10.1289/ehp.1104405. ISSN 0091-6765. PMC 3339468. PMID 22472325.

References

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