NEK9

Serine/threonine-protein kinase Nek9 is an enzyme that in humans is encoded by the NEK9 gene.^[5][6]

NEK9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3ZKE, 3ZKF
Identifiers
Aliases	NEK9, NERCC, NERCC1, Nek8, NIMA related kinase 9, APUG, LCCS10, NC
External IDs	OMIM: 609798; MGI: 2387995; HomoloGene: 13222; GeneCards: NEK9; OMA:NEK9 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.3 Start 75,079,353 bp[1] End 75,127,344 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 D2 Start 85,346,288 bp[2] End 85,386,136 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibia right uterine tube left ovary tendon of biceps brachii right ovary body of uterus canal of the cervix gastrocnemius muscle muscle layer of sigmoid colon stromal cell of endometrium Top expressed in epithelium of lens vastus lateralis muscle iris triceps brachii muscle sternocleidomastoid muscle utricle temporal muscle ureter medial head of gastrocnemius muscle endocardial cushion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity metal ion binding kinase activity protein binding ATP binding protein kinase binding protein serine/threonine kinase activity Cellular component cytosol nucleus cytoplasm centrosome Biological process phosphorylation cell division mitotic nuclear membrane disassembly cell cycle protein phosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 91754 217718 Ensembl ENSG00000119638 ENSMUSG00000034290 UniProt Q8TD19 Q8K1R7 RefSeq (mRNA) NM_033116 NM_001329237 NM_001329238 NM_145138 RefSeq (protein) NP_001316166 NP_001316167 NP_149107 NP_660120 Location (UCSC) Chr 14: 75.08 – 75.13 Mb Chr 12: 85.35 – 85.39 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

NEK9 has been shown to interact with:

• NEK6,^[7][8][9]
• RAN,^[9] and
• SSRP1.^[10]