PPFIA4

Liprin-alpha-4 is a protein that in humans is encoded by the PPFIA4 gene.^[3][4]

PPFIA4
Identifiers
Aliases	PPFIA4, PTPRF interacting protein alpha 4
External IDs	OMIM: 603145; GeneCards: PPFIA4; OMA:PPFIA4 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 203,026,491 bp[1] End 203,078,740 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere right hemisphere of cerebellum cerebellar vermis paraflocculus of cerebellum right frontal lobe primary visual cortex Brodmann area 9 middle temporal gyrus apex of heart cingulate gyrus n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm presynaptic active zone cell surface cytosol synapse intracellular anatomical structure Biological process glutamate secretion neurotransmitter secretion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8497 n/a Ensembl ENSG00000143847 n/a UniProt O75335 n/a RefSeq (mRNA) NM_001304331 NM_001304332 NM_015053 NM_001393950 NM_001393951 NM_001393952 NM_001393953 NM_001393954 NM_001393955 NM_001393956 NM_001393957 n/a RefSeq (protein) NP_001291260 NP_001291261 n/a Location (UCSC) Chr 1: 203.03 – 203.08 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Interactions

PPFIA4 has been shown to interact with:

• ERC2,^[5]
• GIT1,^[5][6] and
• Nuclear receptor coactivator 2.^[7]